The watershed are units controlling hydrological processes and essential for implementation of water resources management policies. The present study aims to integrate the morphometry and land use of the Pajeu river Basin and the Boa Vista micro-basin (headwater of the Pajeu river) using satellite data and a set of remote sensing techniques in open-source software (QGIS). The studied areas are in the semi-arid region of the Pernambuco State, Brazil. Physical morphometric parameters (area, perimeter, axial length, compactness factor, form factor, elongation ratio, and circularity ratio), hydrological parameters (length and distribution of the drainage network, drainage density, hydrographic density, constant of channel maintenance, textural ratio, sinuosity, concentration time, and extension of surface course) and relief (slope and altitude map) were produced. Furthermore, in the micro-basin, we determined the distribution of surface reservoirs using the Modified Normalized Difference Water Index (MNDWI). The Pajeu river basin and the micro-basin have an elongated shape (form factor <0.4 and a capacity coefficient greater than 1.8), approximately 65% of areas with a slope of less than 8%, and moderately developed drainage network; thus, the regions studied are not prone to flooding. However, more than 70% of the basin has soils that have a low infiltration capacity, which, when associated with the conditions of removal of native vegetation, tends to favor the occurrence of floods. Through the integration of land use and morphometry, we found that about 40% of the areas that should be riparian forests are under agricultural activities. A more detailed analysis of the morphometry-coverage-soil-hydrology interactions in watersheds helps understand the hydrological processes and basin management. The presented results can be useful for modeling studies in the basin and for future water resources management plans.