Understanding the characteristics of production safety accidents is a prerequisite for effective defence because these accidents usually lead to casualties and property losses. Therefore, this study addressed these characteristics by using mathematical statistics to analyse 825 accidents in Inner Mongolia in the past 5 years and then developed a set of management strategies for administrators. The results showed that (1) regarding temporal characteristics, production safety accidents occurred more frequently in summer and autumn than in winter, and there were more accidents and deaths on weekends. (2) Regarding spatial characteristics, the frequency and mortality of accidents exhibited spatial differences in prefecture-level cities (e.g., accidents in Baotou and Tongliao were more frequent) and at county scales (e.g., accidents in Horqin and Kundulun were more frequent). (3) Regarding the characteristics of industries with accidents: the high-risk industry was captured, i.e., construction and mining, and accidents mainly consisted of high-altitude falls and mechanical injuries. These findings suggest that administrative and enterprise managers should pay attention to the characteristics of the spatio-temporal distribution patterns, highly hazardous accident types, and high-risk industries and design more suitable strategies for production safety training and supervision to reduce the frequency of accidents and casualties.