Camelids are among the largest wild and domestic faunas in South America and represent one of the most important taxa to pre-hispanic South America human populations. Stable isotope data from these animals play an important role in improving our understanding of human paleodiet, past human-animal interactions, Holocene environmental change, and modern camelid management. This paper presents delta C-13 and delta N-15 values taken from 91 camelid specimens distributed across western Argentina between 30 degrees and 37 degrees S. These samples come from three desert environments (Andean, Patagonia, and Monte) and include both modern and prehistoric samples. Camelid delta C-13 values range between -20.3 parts per thousand and -10.7 parts per thousand, while delta N-15 values vary between 2 parts per thousand and 10.2 parts per thousand. Mean isotope values differ by environmental context, with significant difference in delta C-13 and delta N-15 between Patagonian and Monte or Andean deserts. Camelid isotope values also vary with latitude, altitude and longitude, though differences in delta N-15 are weak, and these geographic differences are tied to climatic variables such as annual mean temperature, annual precipitation, and season of precipitation. When comparing camelid delta C-13 values from Central-western Argentina with those from Northwest Argentina and Patagonia, we see a latitudinal trend of decreasing delta C-13 values, with the most negative values occurring in southern Patagonia and the most positive values in Northwest Argentina. Variation in camelid stable isotope values and their association with particular environmental contexts shows their value as a geographic marker and possibly as a paleoecological proxy. These results highlight the need to consider the geographic origin of camelid isotope values when using them to reconstruct human diet. (C) 2015 Elsevier Ltd. All rights reserved.