Wheat production in semi-arid regions increasingly relies on irrigation to buffer yield losses from recurrent drought, yet soil N2O emissions from combined irrigation and nitrogen (N) fertilization remain poorly quantified, particularly in developing countries such as Morocco. This uncertainty limits the reliability of greenhouse gas inventories and mitigation assessments. We conducted a factorial field experiment in semi-arid Morocco using drip irrigation at 65% (deficit irrigation, DI) and 100% (full irrigation, FI) of crop evapotranspiration (ETc), combined with four N rates (0, 70, 125.5, and 200 kg N ha-1). Grain yield, N recovery efficiency (NRE), cumulative N2O emissions, yield-scaled N2O emissions (YSNE), and emission factors (EF) were quantified. Irrigation regime and N rate significantly affected cumulative N2O emissions and grain yield, although their interaction influenced yield but not emissions, indicating that irrigation independently regulated emission magnitude. FI increased cumulative emissions (0.93 vs. 0.43 kg N2O -N ha-1) and EF (1.1% vs. 0.5%) compared with DI, while yield gains under FI occurred only at 200 kg N ha-1 (3.6 t ha-1). In contrast, DI sustained comparable or higher yields at lower N rates without increasing emissions. Irrigation events of 30-50 mm generated prolonged emission peaks accounting for up to 51% (DI) and 65% (FI) of seasonal losses. These findings demonstrate that irrigation regime strongly controls N2O intensity in semi-arid wheat systems and that EF stratification based solely on climatic classification may underestimate emissions under irrigated conditions.