Effective management of Cynodon dactylon (bermudagrass) is critical for grapevine production in arid environments. A three-year field study (2018-2020) was conducted in a commercial Yaghuti table grape (Vitis vinifera L.) vineyard in southeastern Iran to compare polyethylene mulch (PEM) and four selective herbicides for bermudagrass control and their effects on grape yield and fruit quality. The experiment followed a randomized complete block design in which herbicide treatments and 1 year PEM were rerandomized annually, whereas 2- and 3-year PEM treatments were maintained on fixed plots to evaluate cumulative effects. Among herbicides, clethodim provided the greatest suppression of both above- and below-ground bermudagrass biomass during the first year, followed by haloxyfop R-methyl ester. Multiyear PEM applications resulted in near-complete suppression of bermudagrass biomass by the second consecutive year, with similar levels of control observed in the third year. Grape yield varied among treatments across years. In general, treatments that effectively reduced bermudagrass competition, including clethodim and multiyear PEM, were associated with higher yields relative to the untreated control. In 2020, grapevines under clethodim and multiyear PEM treatments exhibited higher total soluble solids (TSS) at harvest, while titratable acidity (TA) also differed among treatments. These differences likely reflect indirect effects of weed suppression on vine water status and fruit microclimate rather than direct physiological effects of the herbicides. Overall, repeated PEM application provided sustained bermudagrass suppression under arid conditions, whereas clethodim offered effective short-term control. Long-term environmental and economic implications of multiyear PEM use warrant further investigation.