2026 JOURNAL OF THE MEXICAN CHEMICAL SOCIETY 2026 70(卷), 1(期), (null页)
This study is the first to identify polyphenols and flavonoids in ethanolic extracts of aerial parts of Salvia hispanica cultivated under arid conditions using UPLC-MS analysis. Antioxidant activity was evaluated through DPPH, ABTS, PHE, and FRAP tests, while enzymatic activity was assessed via alpha-amylase inhibition. The polyphenol and flavonoid contents were highest in the inflorescences, followed by the leaves and stems. The major compounds identified included oleanolic acid, riboflavin, rutin, naringenin, curcumin, caffeic acid, resveratrol, quercetin, epicatechin, and luteolin. The chelating activity of leaf, inflorescences, and stem extracts ranged from 11.97 to 145.86 mu g mL-1, while alpha-amylase inhibitory activity ranged from 7.66 to 21.25 mu g mL-1. These findings highlight the pharmacological potential of S. hispanica, particularly its antioxidant and antidiabetic properties. This research enhances scientific understanding of Chia's aerial parts, supporting the development of plant-based supplements and medicinal applications for health and wellness.