The integrated analysis of lithofacies, mineralogy and geochemistry of the hemipelagic marine succession exposed in La Cerradura section (South-Iberian Palaeomargin) provides new information to characterise the palaeoenvironmental conditions during the latest Pliensbachian to early Toarcian, including the Jenkyns Event. The area was located within the semiarid climate belt dominated by physical weathering, indeed by high illite content, sporadic record of kaolinite and low Chemical Index of Alteration (CIA) and Plagioclase Index of Alteration (PIA). The end of Pliensbachian, recorded in a densely bioturbated marl-marly limestone alternation, is characterised by enhanced semiarid conditions (increase of quartz/clay ratio, high illite content and aeolian detrital proxies, low values of fluvial detrital proxies, CIA and PIA), confirming physical weathering in the emerged areas. Subsequently, the polymorphum Zone (earliest Toarcian) shows an opposite trend to relatively humid conditions (decreasing quartz/clay ratio and aeolian detrital proxies, and increasing fluvial detrital proxies, CIA and PIA). The Jenkyns Event phase is marked by the record of a negative carbon isotopic excursion, the decrease of carbonate content and the debut of dark marls. This phase begins on an omission surface. The disappearance of trace fossils in the lower part of the Jenkyns Event points to oxygen-depleted conditions in the sea bottom. The climate turns to drier conditions (prevalence of illite, increase of quartz/clay and aeolian proxies, and decrease of fluvial proxies, CIA and PIA). The productivity proxies are consistent with low carbonate content and the biotic crisis of calcareous nannoplankton. After the Jenkyns Event the dark marls are poorly burrowed pointing to progressive improvement of sea bottom oxygenation. Climatic conditions are relatively less arid (decrease of quartz/clay and aeolian proxies, and increase of fluvial proxies, CIA and PIA), evidencing more humid conditions and intensified chemical weathering (sporadic record of kaolinite). However, dominance of illite points to prevalent physical weathering.