Drought is the most important limiting factor in dryland farming. One of the ways to reduce transpiration is antitranspirants application. To achieve the purpose, field and laboratory experiments were conducted to assess the effect of antitranspirant and nitrogen on yield, yield components, and germination traits in wheat. Treatments included different concentrations of antitranspirant, sunflower oil (0%, 5%, and 10%), and different rates of nitrogen (0, 75, and 150 kg ha-1). Nitrogen and antitranspirant were applied at the time of spike emergence, May 15. In the laboratory experiment, the germination traits of seeds produced in the field experiment were assessed using a standard germination test. Results showed that the application of different rates of antitranspirant and nitrogen did not affect leaf and stem yield, seed number per spike, spike weight, seed yield, seed weight, biological yield, or germination traits of the produced wheat seeds. Antitranspirant rate application of 10% reduced harvest index compared to no or 5% application. Factors such as high soil nitrogen fertility, relatively proper soil moisture, and/or treatment application stage can be reasons for the lack of a significant effect of the mentioned treatments.