Soil aggregate stability and carbon-nitrogen content are critical indicators for assessing the vegetation restoration effects. Salix cupularis plays a vital role in rehabilitating desertified alpine meadows on the eastern Qinghai-Tibet Plateau. However, research remains limited about how afforestation influences the soil aggregate stability and associated carbon and nitrogen dynamics. In this study, sandy land (0 years) served as the control, and the spatial time replacement method was used to examine changes in the soil water-stable aggregate composition, stability, organic carbon (OC) and total nitrogen (TN) contents, and density at a 0-60 cm depth after 5 and 10 years of afforestation restoration (Salix cupularis). Ecological restoration significantly enhanced the proportion of macroaggregates (>0.25 mm) in the topsoil (0-20 cm), and improved aggregate stability. After 10 years of restoration, macroaggregates increased by 45.04% and 51.32%, respectively. The average weight diameter and geometric mean diameter of the aggregates increased by 51.32% and 59.53%, respectively. Following restoration, there was a gradual increase in the OC and TN contents in the soil, with the highest increase observed in the 0-10 cm layer (266.67% and 391.67%). The OC and TN of the aggregates also displayed a similar trend. Correlation analysis results indicated a significant positive relationship between the soil OC and TN contents and density, OC content in aggregates of various diameters, and the stability of these aggregates. The Pearson's correlation coefficient for OC in aggregates > 1 mm was the highest. Compared with 5 years, 10 years of recovery were more conducive to the formation of macroaggregates, enhancement in aggregate stability, and the accumulation of OC and TN. Therefore, vegetation restoration on the Zoige Plateau can significantly enhance the soil water-stable aggregate composition and stability and can also increase the soil and OC and TN contents and density, thereby enhancing the soil ecological quality. This study provides fundamental data and theoretical support for rehabilitating desertified grasslands on the eastern Qinghai-Tibet Plateau.