Activated water treatment technology, emerging as a green irrigation strategy for arid sandy soils, demonstrates critical potential in enhancing soil fertility and crop productivity in southern Xinjiang's desert-oasis ecosystems. This study conducted a two-year field experiment to systematically evaluate the impacts of four irrigation treatments: conventional non-activated water (CK), magnetoelectric activated water (MI), micro-nano oxygenated water (IO), and magnetoelectric-oxygenated water (MO). The investigation focused on their effects on rootzone soil moisture distribution patterns, nutrient availability and transformation efficiency, physiological growth indicator, and yield-water use synergies in apple orchards. The results indicate that activated water irrigation promotes soil nutrient absorption and conversion, improving soil fertility, with the soil quality index (SQI) increasing by 10.88 %-32.59 %. Under the conditions of soil salinization and the arid, water-scarce climate of southern Xinjiang, activated water irrigation enhances soil water retention, optimizes soil moisture distribution, and increases the effectiveness of soil moisture. Additionally, activated water irrigation effectively improves the drought resistance of apple trees, with CAT, POD, and SOD activities increasing by more than 10 %, and MDA reducing by up to 10.73 %. Apple yield increased by 12.11 %-35.48 %, and water use efficiency improved by 10.48 %-30.19 %. A synergistic effect was observed between MI and IO. This work establishes an integrated water activation framework for scientific irrigation scheduling in Xinjiang's desert-oasis farmlands and sustainable crop intensification in arid regions facing soil salinization and water scarcity.