West Africa constitutes a hotspot region for both land use change and climate change. Land use change, and high climate variability in this region negatively affect tree growth dynamics, ecosystem functioning and services. In the present study, we assessed the impacts of climate variability on tree growth of Detarium microcarpum Guill. & Perr. and Tamarindus indica L., two Fabaceae woody species with high socio-economic significance in West Africa. In total, we collected 18 stem discs from dead trees of the two species in the South-Sudanian phytogeographic zone in Burkina Faso. The studied species showed well-defined growth ring-boundaries demarcated by marginal parenchyma bands. Cross-dating was successful within disc and within species, and enabled the construction of statistically robust tree-ring index chronologies. The chronologies spanned 45 years (1974 - 2019) and 30 years (1990 - 2019) for D. microcarpum and T. indica, respectively. We found a significant variation in tree growth rates (p-value < 0.05) between D. microcarpum (1.711 +/- 0.491 mm year(-1)) and T. indica (2.613 +/- 0.473 mm year(-1)). Pearson correlation analyses showed that the standard ring-width index for both species positively correlated with total annual precipitation amounts (p-value < 0.05) and major seasonal precipitation (p-value = 0.05). However, no significant correlation was found between ring-width index and temperature related variables. These findings support that precipitation controls tree growth of D. microcarpum and T. indica in the semi-arid savannas of West Africa. Consequently, a decrease in mean annual rainfall in West African region may negatively affect tree growth rate and stand dynamics of the studied species.