This study investigates the bioclimatic requirements and adaptation potential of twelve commercially important table grape cultivars grown in Sar & imath;g & ouml;l, a key viticultural district in Turkey located within the Mediterranean basin. The research is based on long-term meteorological data (1992-2022) obtained from two local meteorological stations (00203455-& Idot;metos 3.3 and 0020345D-& Idot;metos 3.3). To quantitatively assess varietal adaptation and optimal ripening conditions, three critical bioclimatic indices were evaluated: the Heliothermal Index (HI), the Hydrothermal Index (HyI), and the Sum of Effective Temperatures (SET). The findings revealed an average HI value of 5.80 across all cultivars, indicating highly favorable temperature and solar radiation conditions, thus classifying the region as an exceptionally suitable viticultural zone according to international standards. The HyI value of 0.48, calculated for the critical phenological period (May-July), highlighted the necessity for supplemental irrigation despite the region's proximity to Mediterranean climatic influences, confirming its semi-arid characteristics. The long-term average SET for the vegetation period (April 1-October 31) was 2598 degrees C days, revealing significant differences in thermal accumulation requirements among cultivars. For instance, early-ripening cultivars such as 'Trakya & Idot;lkeren' required substantially lower thermal sums (1125 degrees C days) compared to late-ripening ones like 'Autumn Royal' (2297 degrees C days). Phenological data were recorded from the villages of & Ccedil;anak & ccedil;& imath;, Ahmeta & gbreve;a and Af & scedil;ar during the 2019-2020 growing seasons. Overall, the results confirm that all twelve table grape cultivars exhibit suitable adaptation to Sar & imath;g & ouml;l's climatic conditions and can be cultivated successfully in accordance with their bioclimatic needs. However, the findings also underscore the continued need for supplementary irrigation to achieve optimal yield and fruit quality. This study provides valuable quantitative data for climate-smart viticultural planning and varietal selection in Mediterranean-type climate regions, especially in the context of projected climate change impacts on grape production.