Due to a scarcity of freshwater resources, agriculture is dependent on the use of poor quality water for irrigation in arid and semi-arid regions. Hence, the effective use of poor quality water requires pioneering water management and nitrogen fertiliser practices to increase the yield and resource efficiency. This study aimed to investigate the effect of saline water levels, nitrogen fertiliser, and irrigation methods on the eggplant yield, water productivity, NPK uptake, and nitrogen use efficiency (NUE). The experiment was conducted in 2019 and 2020 under drip (IM1) and surface flood irrigation (IM2). The treatments included three saline water levels, i.e., canal water (SW1), electrical conductivity of the irrigation water (ECiw) = 2.5 dS/m (SW2), and ECiw = 5.0 dS/m (SW3) along with the three nitrogen levels of 75% (N1), 100% (N2), and 125% (N3) of the recommended dose of nitrogen. Applica-tion of saline water using IM1 reduced the electrical conductivity (ECe) by 41.8% (SW2) and 34% (SW3) over IM2. The fruit yield, water productivity (WP), NPK uptake, and NUE was increased by 22%, 127.6%, 39.8%, 16.6%, 11.8%, and 23.8% under IM1 over IM2, respectively. A high saline water level under IM2 can cause larger reduction in the fruit yield, NPK uptake, and water use. Applying saline water through IM1 improves the fruit yield, WP, and NUE by 13-32.8%, 104.1-147.3%, and 10.5-35.2%, respectively, as compared to IM2. We found that saline water and N applied by drip improved the eggplant yield, water productivity, and NPK uptake. It is concluded that the irrigation water and nitrogen fertiliser consumption are optimised when saline water is applied through drip irrigation.