The study was conducted at the Arid Zone Research Center (AZRC) Dera Ismail Khan during the 2018-19 crop years on the exogenous application of plant extracts on wheat seed. The trial was laid down in randomized complete block design with three replications. The seven treatments comprised of T-1 (Control), T-2 (Conocarpus lancifolius Engl.), T-3 (Acacia nilotica L.), T-4 (Moringa oleifera Lam.), T5 (Dalbergia sissoo Roxb.), T6 (Eucalyptus camaldulensis Dehnh.), and T7 (Pongamia pinnata L.) plant extracts applied for seed priming of wheat seed variety AZRIC-Dera Ismail Khan. All the physiological agronomic parameters depicted significant variation among the treatment means. The treatment T-4 (Moringa oleifera Lam.) and T-5 (Delbergia sissoo Roxb.) produced 7% and 3.56% higher yield than control (T-1) while these treatments gave (15.1%) higher yield than T6 (Eucalyptus camaldulensis Dehnh.). Hence T-4 (Moringa oleifera Lam.) and T-5 (Dalbergia sissoo Roxb.) may be used as seed priming substances to enhance germination and attain higher yield. Therefore planting of T-4 (Moringa oleifera Lam.) and T-5 (Dalbergia sissoo Roxb.) should be encouraged for having stimulatory effect on wheat grain yield while planting of T-2 (Conocarpus lancifolius Engl.) and T6 (Eucalyptus camaldulensis Dehnh.) should be avoid near the wheat growing field due to inhibitory effect on wheat growth and grain yield.