With respect to the significance of finding methods, which may improve corn (Zea mays L.) yield and quality in the semi-arid areas of the world, an improved method and type of fertilization has been suggested and tested. A two-year field experiment (2016-2017) (split plot) was conducted in the Research Station of Safi-Abad, Dezful, Iran to test the effects of fertilization methods (soil application of fertilizer (N1), foliar application (N2), and fertigation (N3)) and micronutrient use (Fe and Zn at 3 gL(-1)) on the yield and quality of corn plants. Cob (CH) and plant height (PH), weight of 1000 grains (W), corn yield (Y), weight of cob wood (CobWood), cob weight (CobW), number of rows in a cob (NR), number of grains in a row (NG), plant nutrient uptake of Fe and Zn, and grain protein (Pro) were determined. The single or combined effects of the experimental treatments significantly affected the measured parameters. The fertilization method significantly affected corn growth (CH), yield (W, Y, CobWood, and NR) and plant Fe uptake. However, micronutrients were significant on all the measured parameters except Pro. Although the soil method significantly increased plant uptake of Fe and Zn, the foliar application and fertigation methods significantly enhanced corn growth and yield. The combined use of the tested methods may enhance corn yield and quality in the arid and semi-arid areas of the world.