中国循证社会科学协作网

DOI

10.1155/2019/1704816

Top-100 Most Cited Publications Concerning Network Pharmacology: A Bibliometric Analysis

Cuncun Lu ; Zhitong Bing ; Zhijiang Bi ; Ming Liu ; Tingting Lu ; Yangqin Xun ; Zhipeng Wei ; Kehu Yang

作者地址

Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China ; Evidence-based Social Science Center, School of Public Health, Lanzhou University, Lanzhou, China

通讯作者

Zhipeng Wei;Kehu Yang

来源期刊

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE

ISSN

1741-427X

EISSN

1741-4288

出版日期

2019-08-01

卷号

2019

摘要

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE

关键词

ackground. Network pharmacology (NP) has become an increasingly important focus in the drug research field over the past decade. However, no study to date has mapped the current status of NP. Therefore, we performed a bibliometric study to evaluate the top 100 cited papers on NP. Methods. We searched the Web of Science Core Collection from its inception to February 25, 2019, using the terms network pharmacology and systems pharmacology. Key data, including title, publication year, number of citations, authors, countries/regions, organizations, and journals, were retrieved and analyzed using Excel 2016 and VOSviewer 1.6.10. Results. The total number of citations for the 100 cited papers ranged from 21 to 1,238, published in 53 journals, from 2005 to 2017. The top three journals with the most publications on NP were Clinical Pharmacology & Therapeutics (n=8, IF2017=6.544), Journal of Ethnopharmacology (n=8, IF2017=3.115), and PLoS One (n=7, IF2017=2.766). Most published articles were from the USA (n=41) and China (n=35). The most active author was Wang Yonghua from the Northwest A&F University, and of the 100 publications, 14 listing his name. The most frequently used substantive terms included drug discovery, traditional Chinese medicine (TCM), in-vitro, cancer, and cardiovascular disease. Conclusions. The USA and China made the greatest contribution to NP research. The current NP research mainly focused on NP methods (including experimental validation) and using them to explore the molecular mechanisms of TCM for some critical diseases such as cardiovascular diseases and cancers. Furthermore, we believe some guidelines should be developed to regulate NP studies.

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