DOI
10.1097/NCC.0000000000001155
Thirteen Nonpharmacological Interventions for Increasing the Quality of Life in Patients with Advanced Cancer: A Network Meta-analysis
作者地址
Department of Reproductive Medicine Nursing, West China Second University Hospital, Sichuan University/West China Nursing School, Sichuan University
摘要
Background: A variety of nonpharmacological interventions that improve the quality of life of patients with advanced cancer have been difficult for medical staff to select through randomized controlled trials or traditional meta-analyses. Thus, a network meta-analysis is necessary.
Objective: This study used network meta-analysis to analyze the effect of 13 different nonpharmacological interventions on improving the living quality of patients with advanced cancer.
Methods: Five English databases were searched up to January 2019. The search strategy only included terms relating to or describing the intervention.
Results: The study included 13 different nonpharmacological interventions. The overall efficacy was summarized through a holistic study of quality of life. The study found that the combined effect sizes of 13 nonpharmacological interventions crossed the invalid line (weighted mean difference, -13 [95% confidence interval, -33 to 8.5] to 1.7 [95% confidence interval, -18 to 22]), indicating that none of the intervention was significantly different from each other. By evaluating the heterogeneity of this outcome, no significant evidence of heterogeneity ( P > .05) was observed. Probability ranking according to the surface under the cumulative ranking curve showed that there was a great possibility for the CanWalk intervention and structured multidisciplinary intervention to improve outcomes for cancer patients.
Conclusions: Thirteen nonpharmacological interventions did not significantly impact quality of life. Regarding the probability rank, CanWalk intervention may be the most promising way that advanced cancer patients can help themselves to a better life. Because of the limitations of the current studies, the conclusion needs further evidence.
Implications for practice: Nurses should consider recommending moderate physical activity for patients with advanced cancer.
WOS学科分类
Oncology
;
Nursing
WOS关键词
EARLY PALLIATIVE CARE
;
MULTIDISCIPLINARY INTERVENTION
;
METASTATIC CANCER
;
STAGE CANCER
;
TRIAL
;
EXERCISE
;
OUTCOMES
;
END
附件
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433 Thirteen Nonpharmacological Interventions for Increasing the Quality of Life in Patients with Advanced Cancer A Network Meta-analysis.pdf
1.1 MB
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