Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, 730000, China
通讯作者
Xingrong Liu; Kehu Yang
来源期刊
Future Oncology
ISSN
1479-6694
EISSN
1744-8301
出版日期
2020-11-01
卷号
17
期号
9
页码
1105-1124
摘要
Purpose: This study aimed to review the association between antidepressive agent (AD) use and the incidence risk of breast cancer. Methods: CBM, WOS, Embase, PubMed and Cochrane Library were systematically searched in July 2019. The methodological quality of the studies was assessed through the Newcastle–Ottawa Scale. Results: We included 19 studies from six countries or regions with relationships between breast cancer and ADs. Subgroup analysis showed no significant association in nested case–control or case–control studies; however, cohort studies revealed a significant association (odds ratio = 1.11; 95% CI: 1.04–1.17). Conclusions: This meta-analysis indicates that breast cancer was not associated with the use of ADs when considering all types of studies, but an association was observed if we considered cohort studies.
the Fundamental Research Funds for the Central Universities: Evidence Based Social Science Research (grant no. 2019jbkyjc002, lzujbky-2019-ct02 and lzujbky-2020-kb20)