This report is a mid-term evaluation of a UNEP-GEF project. The overall goal of the project is to implement effective, operable, transparent and sustainable National Biosafety Frameworks which cater for national and regional needs, deliver global benefits and are compliant with the Cartagena Protocol on Biosafety in the Caribbean sub-region to ensure that their biodiversity will be less vulnerable to any potential risks from introduced LMOs. The objectives of this Terminal Evaluation were to assess project performance and to determine outcomes and impacts (actual and potential) stemming from the project, including their sustainability, and based on this assessment identify lessons of operational relevance for future project formulation and implementation.