Background: Sjogren's syndrome (SS) is a chronic autoimmune rheumatic disease with an incidence of 0.03 to 0.3%. In recent years, there are an increasing number of randomized controlled trials of traditional Chinese medicine (TCM) for SS. However, there are generally some problems in these published clinical trials: lack of reporting primary or long-term outcomes and the heterogeneous in different clinical trials' outcome. Our study aims to determine the priority outcomes and standard TCM syndromes for all stakeholders and reach agreement on the COS and syndromes to be measured and reported in all future TCM trials in patients with SS. Methods and analysis: A phase-wise refinement approach will be used, consisting of three phases, yet complementary, sub-work phases, whereby each phase will inform the next coming phases. The following are the three phases: (I-a) identifying of a long initial list of outcomes through systematic literature review and semi-structured qualitative interviews and (I-b) identifying an initial list of TCM syndromes through (1) systematic literature review, (2) referencing ancient Chinese medical books, and (3) retrospective studies of medical records; (II) prioritization of outcomes using Delphi survey with different stakeholders, such as health professionals and patients; and (III) through consensus meetings with patients and professionals to agree on the final COS and TCM syndromes. Discussion: We summarized the actions of COS into three points: direct action, indirect action, and final action. After the final COSs is completed, we will publish this research in a journal to promote communication.

Electronic waste (e-waste) has been widely studied by scholars all over the world, but the research topics and development trends in this field are still unclear. This study aimed to explore the status quo, hot topics, and future prospects in the field of e-waste. Data of publications were downloaded from the Web of Science Core Collection. We used CiteSpace V, Histcite, and VOSviewer to analyze literature information. A total of 2800 papers in e-waste research were identified, and the number of publications increased rapidly after 2004. Six thousand five hundred seventy-three authors participated in the e-waste research, but 70.01% of the authors published only 1 article. The most productive country in this field was China (1146 publications), and the most productive institution was the Chinese Academy of Sciences (370 publications). The Waste Management (225 publications) was the most productive journal, and Environment Science & Technology (9704 co-citations) was the most co-cited journal. The main hot topics in e-waste field were management and recycling of e-waste in developing countries, health risk assessment after exposure to organic pollutants, degradation and recovery of waste metal materials, and impact of heavy metals on children's health. The frontier topic was degradation.