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Establishing a core outcome set for neurogenic bladder trials: study protocol for a scoping review and Delphi surveys
Background: Neurogenic bladder (NGB) is a chronic and disabling condition with a high prevalence rate, which can cause economic burden on patients and their families and reduce the quality of life of patients. Researchers have carried out a large number of clinical trials on the effectiveness and safety of different interventions for the treatment of NGB. The published clinical trials of NGB generally suffered from inconsistent and irregular reporting of outcome indicators. To facilitate future research studies of NGB, a core outcome set (COS) is required, which helps translate the results into high-quality evidence. Methods and analysis: This mixed-method project has four phases instrument: in phase 1, a scoping review of the literature to identify outcomes that have been reported in clinical trials and systematic reviews of clinical trials of interventions for NCB; in phase 2, a qualitative component using interviews to obtain the views of NGB patients, families, and their caregivers; in phase 3, Delphi survey among stakeholders to prioritize the core outcomes; and in phase 4, a face-to-face consensus meeting to discuss and agree on the final NBG COS. Conclusions: We will develop a COS that should be reported in future clinical trials of NGB.
期刊论文
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Ecosystem-based approaches to adaptation: strengthening the evidence and informing policy. Research results from the Participatory Plant Breeding and Community Supported Agriculture project, China
Ecosystem-based adaptation (EbA) is the use of biodiversity and ecosystem services as part of an overall strategy to help people to adapt to the adverse effects of climate change and promote sustainable development. This report presents the results of using our Framework for Assessing EbA Effectiveness at the Participatory Plant Breeding and Community Supported Agriculture project, China. The findings will be combined with those from 12 other sites in 11 other countries to help show climate change policymakers when and why EbA is effective.
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