This study investigates the wear behaviors of Inconel 718 (IN718) specimens fabricated by additive manufacturing (AM) and additive-subtractive hybrid manufacturing (ASHM), with a focus on room-temperature milling (RTM) and high-temperature milling (HTM) conditions. The milling process induced severe plastic deformation in the ASHM specimens, resulting in the formation of surface nanocrystalline layers ranging from 10 to 50 μm in thickness. At room temperature, the wear rates of the RTM and HTM specimens were 4.15 × 10 -3 and 4.92 × 10 -3 mm 3·N -1·m -1, respectively, which were approximately reduced by 33% and 20% compared with the AM specimen. This enhancement is primarily attributed to the increased grain boundary density and the introduction of residual compressive stress. At 650 °C, the differences in wear resistance among the specimens diminished, as stable oxide films formed on all surfaces, effectively reducing adhesive wear and mitigating further mechanical degradation.