Semiarid regions are facing overexploitation of groundwater resources to meet irrigation needs. Monitoring the water-energy nexus allows for optimal management of extracted water volumes and consumed energy. A semiarid zone was selected in the Nabeul region of Tunisia where 14 farmers, whose wells were equipped with smart electricity and water meters (SWEMs), for instant monitoring of pumped water volumes and the electrical energy required for irrigation. Monthly data over a period of 8 months were used to study the variations in water volumes and active energy. The analysis of variance classified farmers into four groups based on water volumes and five groups based on active energy. Spatial variability analysis using kriging showed that the northeast zone is the most solicited in terms of water pumping and energy consumption with water volume exceeding 4,000 m(3)/month and active energy reaching 2,500 kWh/month. The prediction of energy based on water volume using machine learning techniques such as random forest and support vector machine was successfully conducted. The tools generated by the methodology were applied to a chosen case in the region to estimate active energy and validate the results obtained. The implemented framework allows for better management of groundwater resources for irrigation. HIGHLIGHTS center dot Irrigation practices require rational management in semiarid regions such as Tunisia. center dot Water supply from groundwater and the energy needed to meet irrigation demands were examined through real-time monitoring. center dot A robust framework integrating combined techniques, including statistical analysis, kriging, and machine learning, has been established to effectively manage water and energy resources in the studied region.