Mapuranga, Johannes ， Song, Lulu ， Zhao, Jiaojie ， Li, Hao ， Zhang, Na ， Yang, Wenxiang
2026-01-01 PLANT STRESS 2026 19(卷), null(期), (null页)
Fusarium crown rot (FCR), caused by Fusarium pseudograminearum, is a soil-borne disease that continuously threatens wheat and barley production worldwide, resulting in substantial yield losses, particularly in semi-arid regions. This review consolidates the latest insights on Fusarium pseudograminearum epidemiology, genetic diversity, host-pathogen interactions, and the mechanisms of resistance. It integrates findings from genomics, transcriptomics, proteomics, and metabolomics. The resistance to FCR is polygenic, it is controlled by multiple quantitative trait loci, which makes breeding for resistance quite challenging. Recent advancements in omics technologies have unraveled key defense genes, signaling pathways, and virulence factors like deoxynivalenol and various effectors. While cultural methods, chemical treatments and biological control agents can help to a certain extent, they only provide partial solutions. Additionally, environmental factors such as drought can aggravate the severity of FCR, underscoring the need for disease management strategies that integrate genetic resistance, agronomic practices, and predictive diagnostics to ensure sustainable management.