It is widely accepted that global cooling since the Late Miocene, particularly the Northern Hemisphere glaciation, has led to a progressive weakening of the East Asian summer monsoon and intensified aridification of Asian inland. Here we present a detailed record of monsoon precipitation over the past 7 Ma, retrieved from two carbonate carbon isotope profiles from the Chinese Loess Plateau (CLP). Our results show that the CLP at the northern edge of the East Asian summer monsoon has been getting wetter rather than drier since similar to 2.7 Ma. This climatic reversal coincided with the increased aridification in Central Asia. Combined with climate model simulations and existing Asia-Pacific hydroclimate records, we suggest that the Westerlies-monsoon interaction forced by the Northern Hemisphere glaciation, induced both a differential evolution of the East Asian summer monsoon at mid- and low-latitudes and an east-west antiphased precipitation change over the mid-latitude Asia since similar to 2.7 Ma. Specifically, the Northern Hemisphere glaciation, and the associated 'Arctic Amplification' intensified and shifted westerlies southward after similar to 2.7 Ma that blocked the northwestward invasion of monsoon moisture, thereby simultaneously drying Central Asia and placing more precipitation to North China. Our findings challenge the prevailing view of the evolution of Asian inland deserts and monsoon, and provide new insights into Asian climate change in the context of interactions between the Westerlies and the East Asian summer monsoon.