Soil salinization in the Mu Us Sandy Land poses significant environmental concerns in China. To investigate the impact of land remediation on improving saline soil (Sodic Solonchak) in this region, this paper focuses on the land remediation project in Dingbian County as the study area. The research selected original cultivated land, saline-alkali land, and newly-added cultivated land across three remediation durations (0, 2, and 4 years) as plots. Classical statistical analysis and canonical correspondence analysis (CCA) were employed to compare the differences in soil physico-chemical properties and enzyme activities among the various plots. The results indicated that the soil organic matter (SOM) content in saline soil increased by 8%, total nitrogen (TN) content by 13%, available phosphorus (AP) content by 102% (P < 0.05), and available potassium (AK) by 21%. Furthermore, SOM, TN, and AK were significantly positively correlated with recovery years. After remediation, four enzyme (catalase, urease, phosphatase and protease) activities, irrespective of remediation time were found to be higher than those in the untreated saline-alkali land. With the exception of catalase, the urease, phosphatase and protease activities in shallow soil were markedly greater than those in deep soil irrespective of remediation time. Moreover, our results demonstrated spatially organized relationships between soil fertility indices, enzyme activity, and plot type. This study concludes that the land remediation project in the Mu Us Sandy Land is both technically feasible and environmentally sustainable for the remediation of saline soil.