Groundwater quality in the semi-arid region of Oum El Bouaghi, Northeastern Algeria, was assessed for irrigation suitability using hydrogeochemical analyses, water quality indices, and GIS techniques. The study analyzed 23 groundwater samples during dry and wet seasons in 2022-2023, several physicochemical parameters were measured. Results revealed neutral to slightly alkaline pH levels, except for one acidic sample, with salinity (EC: 527-5001 mu Scm(-1)) exceeding WHO guidelines, particularly during the dry season due to evaporation and anthropogenic activities. Hydrogeochemical facies showed dominance of Na+-HCO3- and Ca2+-Cl-/SO42- water types, indicating rock-water interactions and evaporation control, as confirmed by Gibbs plots. The IWQI classified water into five categories, with severe restrictions (IWQI < 40) in 13% of samples during the dry season, improving slightly in the wet season. Indices such as SAR, Na%, and RSC indicated low to moderate sodium hazard, while KR and PS highlighted salinity risks in specific areas. Spatial analysis revealed localized pollution hotspots, with the (GPI) identifying minimal to high contamination levels, linked to agricultural and geogenic sources. These findings underscore needs for sustainable groundwater management, including monitoring, optimized irrigation practices, and mitigation of anthropogenic impacts, to ensure long-term agricultural viability in this water-scarce region.