In desert regions, precipitation is one of the significant water sources and a key driver of ecohydrological processes over a range of spatiotemporal scales. When precipitation infiltration was combined with the original soil water, the soil water and plant water use will experience significant dynamic changes, which play an important role in the stability and sustainability of the artificial vegetation. Therefore, soil water dynamics and water use strategies of Haloxylon ammodendron were studied by the hydrogen and oxygen stable isotope technique in this study. The results showed that precipitation in the desert soil was mainly in the form of piston flow, and the precipitation that led to the significant increase of infiltration and recharge was different in different precipitation events. The precipitation of 12.8 and 19.6 mm can make the surface soil water sufficient and continue to penetrate into the deep soil, and the duration of soil water response and the recharge depth were much longer and deeper than those for 4.4 and 7.8 mm events. In addition, the H. ammodendron mainly relied on stable and abundant deep soil water and groundwater. The water use source of H. ammodendron showed no significant response to 4.4 and 7.8 mm precipitation. However, a significant difference in water source proportion occurred before and after 19.6 mm of precipitation. The use proportion of shallow soil water increased from 10.7% to 24.2%, while that of groundwater decreased from 48.8% to 23.2%. Therefore, we concluded that precipitation levels have a major impact on soil water at various depths; in particular, heavy precipitation has a significant impact on deep soil water that deeply controlled the survival of the H. ammodendron plantation. These results offer an essential theoretical foundation for vegetation restoration and sustainability in arid regions.