Deploying large-scale ecological restoration and conservation projects on the Qinghai-Tibetan Plateau (QTP), aimed at achieving maximum of ecosystem multifunctionality within the constraints of ecological conditions, which have transboundary impacts on China and downstream countries. So far, there has no actionable solution to link residents' perceptions and ecosystem management strategies, epistemic injustice occurs throughout the ecosystem management decision-making process, even though residents are the actual participants in them, especially in the QTP, obstructing the realization of social equity. Here, a spatial-explicit Nature-based Equity Space was constructed to quantify how to improve ecosystem multifunctionality by ecological restoration, linking to both residents' perceptions and environmental suitability. The results allude to the potential of enhancing multifunctionality by 4.04 % (3.28 +/- 8.07 % among prefectures) and demonstrate grassland restoration as the most critical strategy and promising pathway. Further, constructed optimized QTP reveal important spatial interactions between local social equity and environmental suitability indicators, where approximately 2.68 million people reside in the synergistic region, 7.14 million residents in the uncoupled region, and even a further 3.28 million people in a "lose-lose" region. The research framework offers operational pathways for spatial allocation aimed at linking residents' perceptions with ecosystem management strategies for the QTP, thereby guiding the direction of regional sustainable development planning to achieve both environmental suitability and social equity.