Improving external validity of epidemiologic cohort analyses: a kernel weighting approach

2020
For various reasons, cohort studies generally forgo probability sampling required to obtain population representative samples. However, such cohorts lack population representativeness, which invalidates estimates of population prevalences for novel health factors that are only available in cohorts. To improve external validity of estimates from cohorts, we propose a kernel weighting (KW) approach that uses survey data as a reference to create pseudoweights for cohorts. A jackknife variance is proposed for the KW estimates. In simulations, the KW method outperformed two existing propensity-score-based weighting methods in mean-squared error while maintaining confidence interval coverage. We applied all methods to estimating US population mortality and prevalences of various diseases from the non-representative US National Institutes of Health-American Association of Retired Persons cohort, using the sample from the US-representative National Health Interview Survey as the reference. Assuming that the survey estimates are correct, the KW approach yielded generally less biased estimates compared with the existing propensity-score-based weighting methods.
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY
页码:1293-1311|卷号:183|期号:3
ISSN:0964-1998
收录类型
SSCI
发表日期
2020
学科领域
循证社会科学-方法
国家
美国
语种
英语
DOI
10.1111/rssa.12564
其他关键词
PROPENSITY SCORE; BANDWIDTH SELECTION; INFERENCE; PARTICIPATION; ADJUSTMENT; BIAS
EISSN
1467-985X
资助机构
Predoctoral Fellowship Research Program of the US National Institutes of Health-National Cancer Institute; Intramural Research Program of the US National Institutes of HealthNational Cancer Institute
资助信息
The first author was funded by the Predoctoral Fellowship Research Program of the US National Institutes of Health-National Cancer Institute. The second and the third authors were supported by the Intramural Research Program of the US National Institutes of HealthNational Cancer Institute.
被引频次(WOS)
5
被引更新日期
2022-01
来源机构
University System of Maryland University of Maryland College Park National Institutes of Health (NIH) - USA NIH National Cancer Institute (NCI)
关键词
Cohort studies Complex survey sample Jackknife variance estimation Kernel smoothing Propensity score weighting Taylor series linearization variance