Survival Rate of Liver Transplantation in Asia: A Systematic Review and Meta-Analysis

Rajabi, A (通讯作者),Golestan Univ Med Sci, Hlth Management & Social Dev Res Ctr, Fac Hlth, Gorgan, Golestan, Iran.;Fararouei, M (通讯作者),Shiraz Univ Med Sci, HIV AIDS Res Ctr, Shiraz, Iran.
2022-10
Background: Liver transplantation is one of the most effective treatments for acute liver failure, chronic liver cirrhosis, and hepatocellular carcinoma. This study was implemented to evaluate the survival rate of liver transplant in Asia. Methods: Studies that investigated the survival rate of liver transplant were selected using a systematic search strategy in the following databases: Medline, Embase, Scopus, ProQuest, ISI Web of Science, and Cochrane to Nov 30th, 2020. Pooled survival rate and 95% confidence intervals were calculated using Der-Simonian and Laird method. Stata 16.0 (Stata Corp, College Station, TX, USA) was used for analysis. Results: One, 2, 3, 5, and 10-year survival rates of liver transplant were estimated to be 85%, 80%, 75%, 73%, and 71%, respectively. The results of the univariate meta-regression for defining the sources of heterogeneity for one-Year survival rate (SR) showed significant effects of bias (ss high risk/ moderate risk =0.059, 95% CI: 0.002, 0.115, P-Value=0.04) and follow up time (ss=-0.0002, 95% CI: -0.0003, -0.00, P-Value=0.02) on heterogeneity. Conclusion: The survival rate of liver transplant in Asia is comparable with the corresponding rate reported in the United States and Europe. This study provides a better view of the efficiency of medical cares, regarding liver transplantation. Medical care be enhanced to increase the survival of liver transplant patients.
IRANIAN JOURNAL OF PUBLIC HEALTH
卷号:51|期号:10|页码:2207-2220
ISSN:2251-6085|收录类别:SCIE
语种
英语
来源机构
Shiraz University of Medical Science; Golestan University of Medical Sciences; University of Southern California; Babol University of Medical Sciences; Urmia University of Medical Sciences; Golestan University of Medical Sciences; Shiraz University of Medical Science
资助机构
Shiraz University of Medical Sciences, Shiraz, Iran
资助信息
This study was supported financially by Shiraz University of Medical Sciences, Shiraz, Iran (Grant Number: 22745). Additional information is available from the corresponding author and can contact the corresponding author.
被引频次(WOS)
0
被引频次(其他)
0
180天使用计数
1
2013以来使用计数
1
EISSN
2251-6093
出版年
2022-10
WOS学科分类
Public, Environmental & Occupational Health
学科领域
循证公共卫生
关键词
Liver transplantation Survival analysis Meta-analysis Asia