Systematic Review of Survival Analysis in Leprosy Studies-Including the Following Outcomes: Relapse, Impairment of Nerve Function, Reactions and Physical Disability

Barbosa, CC (通讯作者),Fundacao Oswaldo Cruz, Aggeu Magalhaes Inst, Dept Collect Hlth, BR-50740465 Recife, PE, Brazil.
2022-10
Leprosy is a public health problem in South American, African and Oceanian countries. National programs need to be evaluated, and the survival analysis model can aid in the construction of new indicators. The aim of this study was to assess the period of time until the outcomes of interest for patients with or exposed to leprosy by means of survival analysis surveys. This review researched articles using the databases of PubMed, Science Direct, Scopus, Scielo and BVS published in English and Portuguese. Twenty-eight articles from Brazil, India, Bangladesh, the Philippines and Indonesia were included. The Kaplan-Meier method, which derives the log-rank test, and Cox's proportional hazards regression, which obtains the hazard ratio, were applied. The mean follow-up until the following outcomes were: (I) leprosy (2.3 years) in the population who were exposed to it, (II) relapse (5.9 years), (III) clinical manifestations before, during and after treatment-nerve function impairment (5.2 years), leprosy reactions (4.9 years) and physical disability (8.3 years) in the population of patients with leprosy. Therefore, the use of survival analysis will enable the evaluation of national leprosy programs and assist in the decision-making process to face public health problems.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
卷号:19|期号:19
收录类别:SCIE
语种
英语
来源机构
Fundacao Oswaldo Cruz; Universidade de Pernambuco (UPE); Fundacao Oswaldo Cruz; Universidade Federal de Pernambuco
资助机构
Coordination for the Improvement of Higher Education Personnel-Brazil (CAPES)(Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES))
资助信息
This study was financed in part by the Coordination for the Improvement of Higher Education Personnel-Brazil (CAPES)-Finance Code 001.
被引频次(WOS)
0
被引频次(其他)
0
180天使用计数
14
2013以来使用计数
14
EISSN
1660-4601
出版年
2022-10
DOI
10.3390/ijerph191912155
学科领域
循证公共卫生
关键词
leprosy epidemiology statistical analysis survival analysis
WOS学科分类
Environmental Sciences Public, Environmental & Occupational Health