Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis

Campus, G (通讯作者),Univ Bern, Dept Restorat Prevent & Pediat Dent, Freiburgstr 7, CH-3012 Bern, Switzerland.;Campus, G (通讯作者),Sechenov Univ, Sch Dent, Dept Pediat Prevent Dent & Orthodont, Moscow 119991, Russia.;Campus, G (通讯作者),Univ Sassari, Sch Dent, Dept Surg Microsurg & Med Sci, Viale San Pietro 3-c, I-07100 Sassari, Italy.
2022-10
A systematic review and meta-analysis were carried out to evaluate the efficacy of silver diamine fluoride (SDF) in controlling caries progression in cavitated primary molars. A search for randomized and non-randomized trials with follow-up > 6 months was performed using PubMed, Scopus and Embase. The Cochrane risk of bias tools were used for the quality assessment. The success rate and odds ratios were chosen to calculate the effect size for the meta-analysis. A total of 792 papers were identified and 9 were selected. A high variability regarding SDF application protocol was found; otherwise, caries arrest was always recorded using visual/tactile methods. Two studies were judged at low risk of bias, six at moderate risk and one at high risk. Data from five studies were aggregated for meta-analysis. Heterogeneity was found moderate (I-2 = 35.69%, p = 0.18). SDF application was found to be overall effective (fixed effect model) in arresting caries progression (ES = 0.35, p < 0.01). In a total of 622 arrested lesions, out of 1205 considered, the caries arrest rate was 51.62% +/- 27.40% (Confidence = 1.55) using SDF >= 38% applied annually or biannually. In conclusion, when applied to active cavitated caries lesions in primary molars, SDF appears to be effective in arresting dental caries progression, especially if applied biannually.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
卷号:19|期号:19
收录类别:SCIE
语种
英语
来源机构
University of Milan; University of Bern; Sechenov First Moscow State Medical University; University of Sassari
被引频次(WOS)
0
被引频次(其他)
0
180天使用计数
1
2013以来使用计数
1
EISSN
1660-4601
出版年
2022-10
DOI
10.3390/ijerph191912917
学科领域
循证公共卫生
关键词
silver diamine fluoride SDF dental caries primary teeth non-invasive treatment minimally invasive treatment
WOS学科分类
Environmental Sciences Public, Environmental & Occupational Health