Toward the goal of more rapid knowledge accumulation via better meta-analyses, this article explores statistical approaches intended to increase the precision and comparability of effect sizes from education research. The featured estimate of the proposed approach is a standardized mean difference effect size whose numerator is a mean difference that has been adjusted for baseline differences in the outcome measure, at a minimum, and whose denominator is the total variance. The article describes the utility and efficiency of covariate adjustment through baseline measures and the need to standardize effects on a total variance that accounts for variation at multiple levels. As computation of the total variance can be complex in multilevel studies, a shiny application is provided to assist with computation of the total variance and subsequent effect size. Examples are provided for how to interpret and input the required calculator inputs.