Background Social distance practices are crucial for outpatient clinics during disease outbreaks and are an effective preventive measure for reducing influenza transmission during such pandemics in people with poor health. Methods This study applies an evidence-based practice (EBP) approach to confirm the effectiveness of social distancing in healthy individuals during an influenza pandemic and employs the induced ordered weighted averaging model to confirm the effectiveness of EBP. The study design, validity, reliability, results, and generalizability focused on discussing three systematic reviews and two cohort studies via the Critical Appraisal Skills Programme (CASP). First, by introducing the patient, intervention, comparison, outcome (PICO) question; second, by establishing the five steps of EBP; third, by utilizing the CASP checklist for the appraisal; and finally, by presenting a conclusion. Results According to the hierarchy of evidence, preferred reporting items for systematic reviews and meta-analyses retrieved five articles for addressing the PICO question. All the evidence demonstrates that social distancing is valuable during influenza pandemics among non-infected individuals. Precise, timely, and robust social distancing implementation can reduce the spread of infection, delay the epidemic peak, and ease the pressure on healthcare resources. Gatekeepers are responsible for guiding individuals through the implementation process for reducing influenza transmission, particularly in densely populated areas. Conclusions Social distance is crucial for outpatient clinics during an epidemic and effectively reduces the spread of infection, delay epidemic peaks, and eases pressure on healthcare resources.